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Mixture of two similarly active and structurally related polypeptides (A1
Hydrazide derivative of fluorescein
differential centrifugation
Plasma levels are reduced in obese humans and low levels are associated with insulin-resistance
anti-Caspase-1 (p20) (human), mAb (Bally-1) Pack Size:100 µg Mixture of two similarly activeCaspase 1 is the best described inflammatory caspase. It processes the cytokines interleukin 1? (IL 1?) and IL 18 and induces pyroptotic cell death. Caspase 1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of
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