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10.3390/ijms22169078 61 HaoY.MiaoJ.LiuW.PengL.ChenY.ZhongQ

We conclude that a single nucleotide substitution was sufficient to switch the repair mechanism, relative to the substate with symmetric G:T mispairs: the ordered, semi-conservative path to repair is now dominant (model 2 favored 18:1 over model 1)

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Moreover, recently Taz -KD has been suggested to affect mitochondriaER contact sites [74], which may further contribute to alterations in the mitochondrial lipid profile [75]