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Consistent with this observation, PERMANOVA analysis demonstrated no statistically significant difference between pre- and post-intervention metabolomes (F = 0.2135, R = 0.0117, p = 0.857), suggesting that the GF-MKD did not induce large-scale global metabolic remodeling

The study concluded that TCC led to faster healing and more granulation tissue formation compared to zinc oxide or no treatment, positioning TCC as a better choice for open-wound management in rabbits [2]