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NAC FOR NEUROLOGIC AND PSYCHIATRIC DISORDERS NAC has been investigated in many neurologic and psychiatric diseases, including neurodegenerative diseases, chronic and neuropathic pain, mood disorders, psychoses, and addiction [5, 9, 98, 99]

48 A large area of cell necrosis appears following APAP overdose

A systematic review and meta-analysis of animal models on the possible link between periodontitis and inflammatory bowel diseases

All chronic diseases, including COVID-19 with the long-COVID-19-syndrome (271), are characterized by the presence of persistent chronic inflammation and sustained generation of reactive oxygen and nitrogen species that when confronted with inadequate antioxidant defenses (likely leading components of anti-inflammaging) precipitate excessive oxidative stress