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Replenishing physiological levels of GHK-Cu has been shown to aid in powerful regenerative and reparative longevity actions including collagen and elastin synthesis, DNA repair, stem cell renewal processes, healthy inflammatory, neurological, and cardiovascular function, and a reset to epigenetic programming

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In this study shRNA-mediated downregulation of LDLR increased the activity of mTOR which could be overcome by inhibiting mTOR