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It has been studied for roles in mitochondrial function, sirtuin activity, and DNA repair

In line with this concept - other than system Xc- inhibitors - dexamethasone only affected ferroptosis induction via FINO2, a drug which iron-dependently generates ROS, but not with other canonical ferroptosis inducers such as direct GPX4 inhibitors

Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinsons disease

For example, obese women demonstrate significantly higher total 24-hour prolactin secretion than normal-weight controls ( Comparative analyses have further revealed that patients with hyperprolactinemia have a higher BMI, fasting plasma glucose, fasting insulin levels, and indices of insulin resistance than normoprolactinemic controls