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In clinical studies, the substance was applied 13 weekly for 412 weeks

Further, the solution formulation or composition provides controlled release of the therapeutic agent to the desired site within the auris interna for some embodiments

This blend has been utilized in preclinical studies examining growth factor receptor signaling, actin polymerization dynamics, copper-peptide extracellular matrix interactions, melanocortin receptor binding activity, and gut epithelial cell function independent of the broader biological effects associated with the individual endogenous counterparts of each compound

Molecules 24, 1123