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Storage and Handling Requirements Proper storage preserves DSIPs potency and prevents degradation that could reduce effectiveness or create safety concerns

Knox S, Downer B, Haas A, Ottenbacher KJ

Sorafenib induces ferroptosis by targeting the cystine/glutamate anti-transport system Xc- [154,155,156,157], an effect that impinges on cystine uptake, thereby preventing subsequent synthesis of glutathione (GSH), the major intracellular antioxidant, preventing GPX4 activation [158, 159], and can trigger ER stress and ferroptosis

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