[DOI] [PubMed] [Google Scholar] 209.Misawa H, Kobayashi N, Soto-Gutierrez A, Chen Y, Yoshida A, Rivas-Carrillo JD, et al
This recognition encouraged preclinical studies aiming to investigate both mechanistic aspects and intervention strategies to characterize and target this biological axis in conditions affecting muscle, brain, the immune system, and metabolic diseases
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The high frequency of the NAT2 and also NAT1 acetylation polymorphism in human population together with ubiquitous exposure to aromatic and heterocyclic amines suggest that and acetylator genotypes are important modifiers of human cancer susceptibility