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GGT is an heterodimeric glycoprotein located on the external plasma membrane of specific cells present in kidney tubules, biliary epithelium and brain capillaries where it hydrolyses GSH into glutamic acid and cysteinyl-glycine

Ichijo H, Nshida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K and Gotoh Y

Proper handling and storage are important for preserving glutathione in its reduced form, minimizing oxidation, and supporting the integrity and reproducibility of laboratory research

Sulforaphane-mediated KEAP1 modification releases NRF2 from degradation and results in NRF2 phosphorylation and nuclear translocation (Figure 2)