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The extracellular L-cysteine/L-cystine redox balance, and thus the synthesis of GSH, is finely regulated by the intracellular conversion of L-cystine into L-cysteine (10), and its impairment is related to oxidative stress and other pathological disorders

The early growth response gene (egr-1) activation observed with BPC-157 treatment may be particularly relevant in diabetic healing

Therefore, in exploring the regulation of redox states for disease treatment, precise targeting of specific DNA repair enzymes can be considered

2012AA022104 and 2012AA021205), the Fundamental Research Funds for the Central Universities (Grant Nos