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The elevation of glutathione levels, observed even 48 h after withdrawal of NFT, rendered cells resistant to different stressors such as the mitochondrial inhibitor rotenone, the redox cycler paraquat, the proteasome inhibitors MG-132 or bortezomib, or high concentrations of NFT

The researchers of a study investigating the potential of the peptide on these factors propose this as a possible mechanism of action for TB-500

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