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Side effects tend to be mild: injection site reactions, some joint stiffness, occasional water retention early on

The Animal Ethics Committee of Nantong University approved all animal studies, which were consistent with the Guide for the Care and Use of Laboratory Animals

337 In noncanonical pyroptosis, caspase-1/11 in mice and caspase-4/5 in human is stimulated directly by LPS in a TLR4-independent manner