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TLR4 is one such PRR that detects damage-associated molecular patterns (DAMPs) created by stressed and dying cells and pathogen-associated molecular patterns (PAMPs) like bacterial lipopolysaccharide (LPS) (Guo et al., 2022

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The enzyme gamma-glutamyltransferase (GGT) in the intestinal lining breaks the glutathione tripeptide into its component amino acids before it reaches systemic circulation