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VGLUT1 glutamatergic presynaptic marker Synapsin Fereira and Rapoport 2002 PSD-95 the postsynaptic marker Nle1-AngIV and Dihexa increase miniature synaptic activity by increasing dendritic spine densities and altering the morphological phenotype of postsynaptic spines in-vitro and may represent the mechanism that underlies facilitated learning observed AngIV analogues (Wright, Stubley et al

doi: 10.3390/ijms17081257

The researchers observed a strong, statistically significant increase in dermal papilla cell growth, along with a higher Bcl2/Bax survival ratio and clear reductions in two deathrelated proteins, caspase3 and PARP, in treated cultures [2]

Researchers have examined the possibility in cell and animal models that IGF-1 could be an effective therapeutic treatment for ALS (Sakowski 2009)