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The underlying mechanism may be related to a key modulator of neutrophil maturation, granulocyte-macrophage colony-stimulating factor (GM-CSF), which was observed to be higher in young adult females than males, followed by diminishing after menopause (53)

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Finally, a third study estimated that a treatment slowing the rate of functional decline among people with dementia by 10% would reduce total average perperson lifetime costs by $3,880 in 2015 dollars ($4,887 in 2024 dollars), while a treatment that reduces the number of behavioral and psychological symptoms by 10% would reduce total average perperson lifetime costs by $680 ($856 in 2024 dollars)

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