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157 ACADSB negatively regulates the expression of GPX4 and glutathione reductase in colon cancer cells, and overexpression of ACADSB increases the concentration of MDA, Fe 2+ and lipid peroxides, inducing cell ferroptosis, and inhibiting the migration and invasion of CRC cells

This is because it helps the body produce melatonin, the hormone that regulates sleep-wake cycles

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Cai H, Liang C, Wang S, Guo J, Wang Y, Yu B, Gao X, Fang S