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Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate

A total of 200 mg/kg of GSH (available in Japan as Tathion, Yamanouchi Pharmaceutical, Tokyo, Japan) was administered intra-venously to 10 patients before cardiopulmonary bypass surgery, and the influence on postoperative renal dysfunction was compared with 9 other patients undergoing the same procedure without GSH administration

Reduced glutathione can activate SH enzymes and others in the body, promoting the metabolism of carbohydrates, fats, and proteins to regulate the metabolic processes of cell membranes