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J Vet Intern Med

What to Expect in Month 2 Peak nausea: Weeks 6-8 worst for most patients, especially mornings Food aversions: Foods you loved suddenly repulsive (especially meat, coffee) Early satiety: Feel full after 3-4 bites, physical discomfort if you push it Fatigue increases: Combination of medication adjustment and reduced calorie intake Bowel unpredictability: Constipation one day, diarrhea the next Mental fog: Some patients report difficulty concentrating Research from the New England Journal of Medicine on incretin therapies shows this peak-and-resolution pattern is universal across GLP-1 and GIP agonists

Pedestrianized areas have attracted a disproportionate number of European and North American newcomers compared to what would be expected in the absence of intervention

But because some research has now shown that long-term use can be safe, some doctors will prescribe phentermine for more than 12 weeks