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In fact, glutathione is present in lung tissue at concentrations about 140 times higher than serum , which helps explain why researchers have focused on local respiratory delivery rather than relying only on systemic routes like oral or IV use, as noted in the ClinicalTrials.gov record for the inhaled glutathione cystic fibrosis trial

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Although further confirmation in neonatal animals is critical, these data may indicate that glutamine plays a role in promoting a more balanced T H 1/T H 2 immune system in the neonatal period