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Furthermore, a study shows that oridonin (ORI), the main active component derived from the Chinese herbal plant Rabdosia rubescens, boosts the anti-proliferative effect of RSL3 on breast cancer cells by facilitating ferroptosis

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There are 12 putative -helical TM domains and a large extracellular loop between the IX and X TM domains, which possess intacellularly localized N- and C- termini (Liang et al