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Heres what we recommend for elderly patients: Start with 1000 mcg of vitamin B12 weekly for 4-6 weeks Then, give 1000 mcg every 1-3 months, depending on how theyre doing Keep an eye on their vitamin B12 levels, blood counts, and brain function A study in the Journal of Gerontology stressed the need for B12 in older adults

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NNMT is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH)