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753,754 The expression of spermidine/spermidine N1-acetyltransferase 1 (SSAT1) is upregulated in the cortical penumbra of transient MCAO/R mice, and SSAT1 knockdown reduces cortical iron content, ROS production and 4-HNE levels, and alleviates I/R-induced cerebral infarction and nerve injury

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To explore the functional relevance of these DEGs, gene ontology (GO) enrichment analysis was conducted, revealing that the altered genes were primarily involved in immune response regulation, cytokine production, oxidative stress response, and mitochondrial functions

Further down the intestinal tract, GSH levels in digesta were significantly higher in the HGSH group as compared to the LGSH group