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When utilised as a protoype cryoprotective agent, BPC 157 has been seen to positively control blood vessel function in respsonse to performation and obstruction, thus re-establishing blood flow (Sikiric et al

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This prevents tumor endothelial cells from properly responding to physiological stimuli (25)

Tissue Eng B Rev 17:165176 Lovric-Bencic M, Sikiric P, Hanzevacki JS, Seiwerth S, Rogic D, Kusec V, Aralica G, Konjevoda P, Batelja L, Blagaic AB (2004) Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse