Regarding endocrine disruption, common flavonoids such as genistein, quercetin, and apigenin have been reported to activate estrogen receptor signaling pathways at low concentrations, thereby exhibiting phytoestrogen-like activity (Zhang and Wu, 2022)
The qPCR cycling conditions were as follows: an initial denaturation at 95 C for 15 min, followed by 30 cycles of 95 C for 7 s and 58 C for 10 s, and a final extension step at 95 C for 5 min, then 40 cycles of 95 C for 15 s and 58 C for 30 s
Subcutaneous Protocol Table (1 Injection Daily or Every Other Day) (Assumes 200 mg/mL concentration 1 unit = 2 mg on a U-100 syringe) One vial (~1500 mg) lasts about 78 injections using this protocol
Numerous other studies have investigated the potential chemo-potentiating effects of TQ with diverse classes of chemotherapeutic drugs (summarized in Table 1) including anti-estrogen (e.g., tamoxifen), topoisomerase-I inhibitor (e.g., topotecan), and microtubule disrupting agents (Rajput et al., 2013