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Decades of preclinical and limited clinical research suggest that DSIP may enhance slow-wave sleep, support neuroendocrine function, and offer protective effects in certain physiological contexts, including post-stroke recovery and age-related cellular stress

Trivedi DK, Gill SS, Yadav S, Tuteja N

Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017