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The evidence base is largely preclinical (animal and cell) research on the individual components, supplemented by practitioner-derived protocols

The aim was to provide supplement options that had been tested by a third-party to significantly reduce the risk of players failing drug tests due to tainted supplements

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However, when comparing the reductive half-reaction of the C31S variant (Figure 6) to that of the U597C enzyme it is immediately apparent that, although the reduction of this disulfide is proposed to be necessary for the reduction of GSSG, this process is not captured in the transient state kinetic data presented