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Allende-Vega et al., 2022)

Effect of chronic renal failure on cardiac contractile function, calcium cycling, and gene expression of proteins important for calcium homeostasis in the rat

As the only extracellular enzyme in the GPx family, GPx3 is an essential enzyme that is responsible for removing ROS products during normal metabolism or oxidative damage in healthy tissues [76]

168 Additionally, senescent neutrophils can accumulate at pre-metastatic sites for lung metastasis in breast cancer patients, forming neutrophil extracellular traps that effectively ensnare tumor cells and facilitate lung metastasis