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Description

Mechanistically, low CFTR expression impairs the expression of the chloride ion-sensitive with-no-lysine kinase 1 (WNK1) protein, thereby leading to activation of transient receptor potential cation vanilloid 4 (TRPV4)

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Additionally, ATG12 can support apoptosis via direct inhibition of Bcl-2 and Mcl-1 [307]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 222.Azargoonjahromi A

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