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Plant Cell Physiol 40:273280 Zaharieva TB, Gogorcena Y, Abada J (2004) Dynamics of metabolic responses to iron deficiency in sugar beet roots

PMID 10439960

Although many of these studies have based their findings on peripheral markers of abnormal metabolism, many studies have documented some of these same abnormalities in the brain of individuals with ASD, including mitochondrial dysfunction and oxidative stress (30) and one study has demonstrated a link between oxidative stress, inflammation, and mitochondrial dysfunction in the brain of individuals with ASD (23)

You hit 40 and suddenly your metabolism decided to retire early without giving you notice