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Genetic analysis of glutathione S-transferase A1 polymorphism in the Chinese population and the influence of genotype on enzymatic properties

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Creation of two opposite-acting yeast-based assays for high throughput screening for ChaC1 inhibitors Since neither the in silico strategy nor the use of synthetic analogues could provide a tentative lead as an inhibitor against the ChaC1 enzyme, a random chemical compound library screening strategy was adopted