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Together, they are frequently studied in laboratory environments for their potential synergistic effects on cellular signaling, tissue regeneration pathways, and inflammatory response modulation

Anastomoses between two defects in the corresponding tissues (i.e., in esophagus and skin (Skorjanec et al., 2009), duodenum and skin (Skorjanec et al., 2015), colon and skin (Klicek et al., 2008), colon and bladder (Grgic et al., 2016), and rectum and vagina (Sikiric et al., 2020a)

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These include the bacteriostatic water storage conditions, handling, and the period since its first use