Journal of Neural Transmission, 113(6), 855-868
Consistent with the evidence presented we suggest a positive effect towards re-establishing IGF-1 levels by substitutive therapy only to physiological levels, never above them
In summary, neuropathy, vascular damage, and endocrine disruption caused by diabetes are the primary causes of male sexual dysfunction, leading to issues such as ED, ejaculatory dysfunction, and reduced libido in approximately 90% of diabetic men
Noncontrolled Trial JAMA Neurol 77:427434 Nabavi SF, Sureda A, Dehpour AR, Shirooie S, Silva AS, Devi KP, Ahmed T, Ishaq N, Hashim R, Sobarzo-Snchez E et al (2018) Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration