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doi:10.1007/s00441019030168

147,148 In one placebo-controlled trial in 46 men with low sperm numbers, those who received ashwagandha root extract (standardized to contain at least 5% withanolides), at 225 mg three times daily for 90 days, had a 167% increase in sperm number, 57% increase in sperm motility, and 53% increase in semen volume, while those who received placebo had little change in these parameters

These would include, for example, antacid medications that inhibit the bodys production of stomach acid, anti-cholesterol medications that block the production of cholesterol, and selective serotonin reuptake inhibitors (SSRIs) that block the uptake of serotonin to treat depression

Deviating from the recommended dosage, whether intentionally or accidentally, can compromise the therapeutic efficacy and lead to unintended consequences