STABLE GASTRIC PENTADECAPEPTIDE BPC 157 HEALS CYSTEAMINE-COLITIS AND COLON-COLON-ANASTOMOSIS AND COUNTERACTS CUPRIZONE BRAIN INJURIES AND MOTOR DISABILITY 2Department of Pathology, Medical Faculty, University of Zagreb, Zagreb, Croatia INTRODUCTION Several important findings recently appear in inflammatory bowel disease (IBD) and ulcerative colitis (1, 2) in particular, alterations of the brain-gut interactions ("brain-gut axis") (3) while stable gastric pentadecapeptide BPC 157 particular effects on nitric oxide (NO)-system (4), nonsteroidal anti-inflammatory drugs (NSAIDs)-toxicity, peripheral and central (5), gastrointestinal tract (6, 7) and wound-healing, and blood vessels (8), were recently reviewed
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However, it has been reported that the aryloxyl radicals are sometimes unstable showing a prooxidant behavior (Bors et al
Prebiotics, defined as selectively fermented components that lead to specific changes in the composition and/or activity of the gastrointestinal microbiota, thereby conferring health benefits to the host (165, 166), offer a promising strategy
