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Anaemia can occur if the red blood cell count drops

Key enzymes involved in the GABA shunt pathway, namely GAD, SSADH, and GABA-T play crucial roles in these processes

Subsequently, Yagoda and Yangs groups demonstrated that iron chelators could inhibit this type of cell death, discovered that Ras-selective lethal 3 (RSL3) mimicked Erastins effects in RAS-mutant cells, and found that elevated levels of ROS and iron were closely associated with RAS signaling (Yagoda et al., 2007