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376,722,723,724 Telomere shortening, another hallmark of aging, contributes to the senescent phenotype

Bedford's outdoor culture plays a role too

doi: 10.1016/j.bbi.2017.10.017 137 KenkhuisBSomarakisAde HaanLDzyubachykOMEIJde MirandaNet al

In particular, the fungal PP motif (Mompen et al., 2018), recently complemented by the structure of RIPK3 solved by cryo-EM in combination with SSNMR (Wu et al., 2021), and it remains to be solved if the sequence similarity between fungal and mammals necroptotic amyloid motifs translate into structure similarity