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[6] [8] Thymosin beta-4 has also been reported to down-regulate inflammatory cytokines and reduce apoptosis and fibrosis effects framed differently from BPC-157s cytoprotective, nitric-oxide-centered profile

This reshapes their intrinsic capacity for radiotherapy resistance while also establishing an immunosuppressive microenvironment, which are both efficiently targeted by (neo)adjuvant sertraline treatment

As of December 2023, out of the 250 current active pharmacological and non-pharmacological NIH clinical trials there is no specific mention of trials stated to target microbes (National Institute on Aging, 2024)