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Oxidized Redox State of Glutathione in the Endoplasmic Reticulum

HTN: hypertension, BP: blood pressure, SBP: systolic blood pressure, DBP: diastolic blood pressure, FMD: Flow-Mediated Dilation, CVD: cardiovascular, CKD: chronic kidney disease, MDA: Malonyl dialdehyde

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For example, enzymes SOD, Cat, and GPx, and transition-metal binding proteins, such as transferrin, ferritin, and ceruloplasmin, inactivate free radicals ( 2 O 2 levels, GPx also participates in detoxification by converting lipid peroxides to the corresponding alcohols