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Extremely high plasma glycine concentrations may lead to hyperglycinemia and, via catabolism, hyperammonemia, potentially causing neurological symptoms such as headache or confusion-though such events are exceedingly rare outside massive irrigant absorption

[DOI] [PubMed] [Google Scholar] 451

Following the nerve transection, heparin was delivered through the tail vein and the animal was monitored under anesthesia for an hour to simulate the transport time it takes to get treatment in cases of traumatic peripheral nerve damage