Clone MD106 Isotype IgG1k Host species Mouse Species Reactivity Human Cellular Localization Cytoplasm Positive Control Kidney, liver or placenta tissues, HeLa, MCF7 or HepG2 cells Applications IHC, WB Intended Use Research Use Only
10.1055/a-2084-3561 76 MalekN.GrossetD
IFN- locally increases levels of CXCL9 and CXCL10 in the skin and serum of vitiligo patients, which in turn attracts pathogenic T cells expressing the CXCR3A receptor.18 A predominant lymphocytic infiltrate of CD8+ T cells has been observed in perilesional skin, correlating with disease activity.3 In vitiligo patients, CD8+ T lymphocytes recognize specific melanocyte antigens (MelanA, tyrosinase, gp100, tyrosinase-related proteins 1 and 2, Mart-1)
All samples obtained by the Blood Service Biobank were in frozen 200 ul aliquots, anonymized, coded and accompanied with gender, age, height and weight information