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This does not necessarily exclude BDNF from mediating the improved memory of elderly subjects maintained on dietary restriction as peripheral BDNF levels were reported and neural BDNF levels remained unknown [182]

Effect sizes seen in animal studies frequently do not replicate in human trials

Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

The combination therapy also mitigated common side effects often associated with benzodiazepines, including memory loss, attention deficits, asthenia, and drowsiness [15]