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doi: 10.3389/fsysb.2025.1561047

Correct cannula placement was evident in all rats utilized in this study

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Methylphenidate affects everyone differently, but the most common side effects may include: euphoria and heightened sense of well-being high body temperature cardiovascular system failure hostility or paranoia irregular or increased heartbeat and palpitations increased blood pressure and respiration increased activity, talkativeness and alertness reduced fatigue, drowsiness and appetite dry mouth, dilated pupils, nausea and headaches increased sex drive feelings of cleverness, great competence, and power