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Growth Factor Receptor Expression: It may increase the expression of receptors for other growth factors, making the injured tissue more responsive to the body's natural healing signals

Over multiple draws from a single vial, dead volume losses accumulate

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A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria