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Various cationic polymers, including polyethylenimine (PEI), polyamidoamine dendrimers (PAMAM), poly-L-lysine (PLL), poly--aminoester (PBAE), and poly-lactic-co-glycolic acid (PLGA), have been developed for this purpose (Fig

In other embodiments, PLGA copolymers with polyethylene glycol (PEG) are suitable polymeric matrices for the formulations disclosed herein

Therefore, it is presumed that alterations in the microbiome may be detrimental to the horse, resulting in abnormal intestinal permeability and subsequent diarrhea, endotoxemia, and laminitis [117,118]

Conventional Treatment : Polypharmacy or experimental neuromodulation