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Group I mGluRs are associated with NMDA receptors and therefore regulate the NMDA receptor-mediated LTP and LTD [27]

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In addition, the mimics may be used for the treatment of "depression", by which we mean major depressive disorder (MDD) (also known as recurrent depressive disorder, clinical depression, major depression, unipolar depression, or unipolar disorder) and also depression that is characteristic of bipolar disorder, etc