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doi: 10.1016/j.ccell.2019.04.002 70 LeiGZhangYKoppulaPLiuXZhangJLinSHet al

However, recapitulating in vitro the architecture and cellular interactions of complex tissues such as the human liver remains an unmet challenge

The standard antidote for APAP overdoses given in Emergency Departments is N-acetylcysteine (NAC) which is given to increase GSH production

Superoxide (O 2 - ) anions are scavenged by redox enzyme superoxide dismutase (SOD), whereas H 2 O 2 by catalase (CAT), glutathione (GSH), GSH-peroxidase (GPx), thioredoxin peroxidase (Trx), and peroxiredoxins (Prdx) 556