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Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer

cAMP/PKA Steroidogenic Signalling In primary mouse Leydig cell cultures, hCG was found to be approximately 10-fold more potent than LH in cAMP recruitment, and slightly but significantly more potent in cAMP-dependent Erk1/2 phosphorylation though no significant differences were observed at the level of downstream steroidogenic events including Creb phosphorylation, Stard1 gene expression, and testosterone synthesis

10.1021/acssynbio.1c00402

Microbial peptides, including mycobacteria-derived muramyl dipeptide (MDP), FK565, and Streptomyces -derived bestatin have shown anticancer properties [28]