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WB and chromatin immunoprecipitation (ChIP) analyses revealed that p53 overexpression can target and negatively regulate biological activity by binding to the SLC7 A11 promoter [35], indicating that p53 can mediate ferroptosis through multiple pathways at the same time

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Biochemical studies on the cardioprotective effect of glutamine on tissue antioxidant defense system in isoprenaline-induced myocardial infarction in rats

This heightened membrane tension activates Piezo1 and transient receptor potential (TRP) mechanosensitive ion channels, while simultaneously inactivating membrane Na+/K+-ATPases