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Description

It is a prodrug and its active metabolite is 7-ethyl-10-hydroxycamptothecin (SN-38)

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This stability eliminates the need for protective carriers that other therapeutic peptides require

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Dysbiosis disrupts intestinal homeostasis, increasing permeability (leaky gut) and enabling LPS translocationthe initiating event for peripheral inflammation

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The first part of this study examines lysine sources, requirements, transport through the plasma membrane, lysine catabolism, and its disorders

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